THERAPEUTIC VACCINES FOR GENITOURINARY MALIGNANCIES

Therapeutic Vaccines for Genitourinary Malignancies

The field of genitourinary malignancies has been a showcase for therapeutic cancer vaccine success since the application of intravesicular Bacillus Calmette-Guerin (BCG) for bladder cancer medford infraction in the 1970s and enjoyed a renaissance in 2010 with the US Food and Drug Administration (FDA) approval of sipuleucel-T for prostate cancer.Sev

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Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcriptional activity.

CCDC6 was originally identified in chimeric genes as caused by chromosomal translocation involving the RET protooncogene in some thyroid tumors.Recognised as a 65 kDa pro-apoptotic phosphoprotein, CCDC6 has been tonies jj audio play character from cocomelon enrolled as an ATM substrate that contribute to protect genome integrity by modulating PP4c

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